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||What Are Its Effects?
As a result of the malformation of the pulmonary valve, the pulmonary artery becomes greatly enlarged and may interfere with breathing by compressing the bronchial tubes. The large ventricular septal defect allows the mixing of oxygen-rich and oxygen-poor blood in the two ventricles, often with an excess of flow to the lungs. If also associated with some degree of pulmonary valve stenosis, a significant amount of the poorly oxygenated blood enters the systemic circulation from across the VSD, resulting in "blueness" or cyanosis.